4,4'-Dimethoxytrityl chloridewaa nucleoside awood leh iyo kooxda nucleotide ilaalinta iyo baabi'inta wakiilka.
La mid ah:DMT-Cl
Lambarka CAS:40615-36-9
Guryaha
Foomamka Kiimikada
Miisaanka Molecular
Heerkulka Kaydinta
Meesha dhalaalaysa
daahirnimo
Dibadda
C21H19ClO2
338.82 g/mol
2 ~ 8℃
120-125 ℃
≥98%
Crystalline casaan
Sida qaybaha muhiimka ah ee silsiladaha nucleic acid, nucleosides iyo nucleotides waxay door muhiim ah ka ciyaaraan gudbinta macluumaadka hidda-socodka.Si kastaba ha noqotee, fal-celintooda kiimikaad iyo hoos-u-dhac sahlan awgeed, nucleosides iyo nucleotides waxay u baahan yihiin reagen gaar ah si ay u ilaaliyaan inta lagu jiro isku-dhafka.DMTCl4'Dimethoxytrityl (DMTCl) waa koox aad waxtar u leh ilaalinta iyo baabi'inta wakiilka taas oo isbedelay ilaalinta nucleosides iyo nucleotides inta lagu guda jiro synthesization.
DMTCl waa wakiilka ilaalinta hydroxyl kaas oo si xushmad leh ula falgala kooxaha hydroxyl ee nucleosides iyo nucleotides inta lagu guda jiro synthesis si ay u sameeyaan koox ilaalin ku meel gaar ah oo ka hortagaysa nucleosides iyo nucleotides inay la falgalaan kiimikooyinka kale.Kooxdan ilaalinta ku meel gaadhka ah si fudud ayaa looga saaraa ka dib marka la isku daro, taasoo ka tagaysa nucleosides saafi ah ama nucleotides.
Feejignaanteeda wanaagsan iyo doorashadeeda awgeed.DMTClwaxaa si weyn loogu isticmaalaa koox ahaan ilaalinta iyo baabi'inta wakiilka ee isku-darka DNA, RNA iyo asiidhyada kale ee nucleic.Waxay si gaar ah faa'iido u leedahay isku-darka oligonucleotide halkaasoo xakamaynta saxda ah ee booska nucleotide iyo isku xigxiga loo baahan yahay.
Marka lagu daro u shaqaynta sidii koox difaac iyo baabi'iye ah, DMTCl waa difaac awood leh oo hydroxyl ee nucleosides iyo nucleotides.Waxay ka ilaalisaa kooxaha hydroxyl ee nucleosides iyo nucleotides ka oksaydhka, dhimista, iyo falcelinta kale ee waxyeello u geysan karta inta lagu jiro isku-dhafka.
Marka la soo koobo,DMTCl4 4' dimetoxytritylwaa qalab muhiim u ah isku dhafka nucleosides iyo nucleotides.Dhaqdhaqaaqeeda aadka u wanaagsan, xulashada iyo isku-dhafka ayaa ka dhigaya koox ku habboon ilaalinta iyo baabi'inta wakiilka iyo wakiilka ilaalinta hydroxyl ee DNA, RNA iyo isku-darka acid nucleic kale.Haddii aad u baahan tahay ilaalin tayo sare leh oo la isku halayn karo ee nucleosides iyo nucleotides inta lagu jiro synthesis, ha ka fogaan DMTCl.
Waqtiga boostada: Jun-08-2023